DiaVacs Immunotherapy – Cell-Based Type 1 Diabetes and SARS-COV2

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

A new generation of Ca2+ indicators with greatly improved fluorescence properties. A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+. The compounds combine an 8-coordinate tetracarboxylate chelating site with stilbene chromophores. Incorporation of the ethylenic linkage of the stilbene into a heterocyclic ring…

Dendritic cells and the control of immunity.

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Experimental introduction of RNA into cells can be used in certain biological systems to interfere with the function of an endogenous gene. Such effects have been proposed to result from a simple antisense mechanism that depends on hybridization between the injected RNA and endogenous messenger RNA…

Inflammation and cancer.

Studies on transformation of Escherichia coli with plasmids. Factors that affect the probability of genetic transformation of Escherichia coli by plasmids have been evaluated. A set of conditions is described under which about one in every 400 plasmid molecules produces a transformed cell. These conditions include cell growth in medium containing elevated levels of Mg2+, and incubation of…

A rapid alkaline extraction procedure for screening recombinant plasmid DNA.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. 1. The extracellular patch clamp method, which first allowed the detection of single channel currents in biological membranes, has been further refined to enable higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches. 2. A description of a convenient method…

SARS-CoV-2 Rapid Antigen Test

The SARS-CoV-2 Rapid Antigen Test is a rapid and reliable chromatographic immunoassay for the qualitative detection of specific SARS-CoV-2 antigens present in the human nasopharynx. This test is an aid to detect the SARS-CoV-2 virus antigen in people suspected of COVID-19. This product is strictly designed for professional use in laboratory and point-of-care environments. Severe…

Lipid Peroxidation (MDA) Assay Kit (C/F)

The quantification of lipid peroxidation is essential to assess oxidative stress in pathophysiological processes. Lipid peroxidation forms malondialdehyde (MDA) and 4-hydroxy nominal (4-HNE), as natural by-products. The measurement of the end products of lipid peroxidation is one of the most accepted tests to determine oxidative damage. The BioVision Lipid Peroxidation Assay Kit provides a convenient…

Syphilis Mixed Titer Panel

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Hallmarks of cancer: the next generation.

Hallmarks of cancer: the next generation. The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating invasion and metastasis. Underlying…

Transformation of intact yeast cells treated with alkali cations.

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. The considerable therapeutic potential of human multipotent mesenchymal stromal cells (MSC) has generated markedly increasing interest in a wide variety of biomedical disciplines. However, investigators report studies of MSC using different methods of isolation and expansion, and different approaches to characterizing the cells.…