A new generation of Ca2+ indicators with greatly improved fluorescence properties.

• Morgan
• June 25, 2021April 28, 2021
• 0

A new generation of Ca2+ indicators with greatly improved fluorescence properties. A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+. The compounds combine an 8-coordinate tetracarboxylate chelating site with stilbene chromophores. Incorporation of the ethylenic linkage of the stilbene into a heterocyclic ring…