
Hallmarks of cancer: the next generation.
Morgan
- 0
Hallmarks of cancer: the next generation.
The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating invasion and metastasis. Underlying these hallmarks are genome instability, which generates the genetic diversity that expedites their acquisition, and inflammation, which fosters multiple hallmark functions.
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Conceptual progress in the last decade has added two emerging hallmarks of potential generality to this list-reprogramming of energy metabolism and evading immune destruction. In addition to cancer cells, tumors exhibit another dimension of complexity: they contain a repertoire of recruited, ostensibly normal cells that contribute to the acquisition of hallmark traits by creating the “tumor microenvironment.” Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described. The method provides a pure preparation of undegraded RNA in high yield and can be completed within 4 h. It is particularly useful for processing large numbers of samples and for isolation of RNA from minute quantities of cells or tissue samples.
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming. Here, we demonstrate induction of pluripotent stem cells from mouse embryonic or adult fibroblasts by introducing four factors, Oct3/4, Sox2, c-Myc, and Klf4, under ES cell culture conditions. Unexpectedly, Nanog was dispensable. These cells, which we designated iPS (induced pluripotent stem) cells, exhibit the morphology and growth properties of ES cells and express ES cell marker genes.
Subcutaneous transplantation of iPS cells into nude mice resulted in tumors containing a variety of tissues from all three germ layers. Following injection into blastocysts, iPS cells contributed to mouse embryonic development. These data demonstrate that pluripotent stem cells can be directly generated from fibroblast cultures by the addition of only a few defined factors.
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.
The steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A computer-solved model has been used to predict the homeostatic concentrations which arise from varying degrees beta-cell deficiency and insulin resistance. Comparison of a patient’s fasting values with the model’s predictions allows a quantitative assessment of the contributions of insulin resistance and deficient beta-cell function to the fasting hyperglycaemia (homeostasis model assessment, HOMA). The accuracy and precision of the estimate have been determined by comparison with independent measures of insulin resistance and beta-cell function using hyperglycaemic and euglycaemic clamps and an intravenous glucose tolerance test.
The estimate of insulin resistance obtained by homeostasis model assessment correlated with estimates obtained by use of the euglycaemic clamp (Rs = 0.88, p less than 0.0001), the fasting insulin concentration (Rs = 0.81, p less than 0.0001), and the hyperglycaemic clamp, (Rs = 0.69, p less than 0.01). There was no correlation with any aspect of insulin-receptor binding. The estimate of deficient beta-cell function obtained by homeostasis model assessment correlated with that derived using the hyperglycaemic clamp (Rs = 0.61, p less than 0.01) and with the estimate from the intravenous glucose tolerance test (Rs = 0.64, p less than 0.05).
The low precision of the estimates from the model (coefficients of variation: 31% for insulin resistance and 32% for beta-cell deficit) limits its use, but the correlation of the model’s estimates with patient data accords with the hypothesis that basal glucose and insulin interactions are largely determined by a simple feed back loop.
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.
A tetrazolium salt has been used to develop a quantitative colorimetric assay for mammalian cell survival and proliferation. The assay detects living, but not dead cells and the signal generated is dependent on the degree of activation of the cells. This method can therefore be used to measure cytotoxicity, proliferation or activation.
The results can be read on a multiwell scanning spectrophotometer (ELISA reader) and show a high degree of precision. No washing steps are used in the assay. The main advantages of the colorimetric assay are its rapidity and precision, and the lack of any radioisotope. We have used the assay to measure proliferative lymphokines, mitogen stimulations and complement-mediated lysis.
Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.
The Agrobacterium vacuum infiltration method has made it possible to transform Arabidopsis thaliana without plant tissue culture or regeneration. In the present study, this method was evaluated and a substantially modified transformation method was developed. The labor-intensive vacuum infiltration process was eliminated in favor of simple dipping of developing floral tissues into a solution containing
Agrobacterium tumefaciens, 5% sucrose and 500 microliters per litre of surfactant Silwet L-77. Sucrose and surfactant were critical to the success of the floral dip method. Plants inoculated when numerous immature floral buds and few siliques were present produced transformed progeny at the highest rate. Plant tissue culture media, the hormone benzylamino purine and pH adjustment were unnecessary, and Agrobacterium could be applied to plants at a range of cell densities. Repeated application of Agrobacterium improved transformation rates and overall yield of transformants approximately twofold.
Covering plants for 1 day to retain humidity after inoculation also raised transformation rates twofold. Multiple ecotypes were transformable by this method. The modified method should facilitate high-throughput transformation of Arabidopsis for efforts such as T-DNA gene tagging, positional cloning, or attempts at targeted gene replacement.
Betacellulin, human |
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RC218-23 | Bio Basic | 5ug | EUR 125.26 |
Rabbit Polyclonal antibody Anti-CRBN |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
Anti-Betacellulin/Btc Antibody |
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A02171-1 | BosterBio | 100ug/vial | EUR 400.8 |
Recombinant Human Betacellulin |
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7-00223 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Betacellulin |
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7-00224 | CHI Scientific | 20µg | Ask for price |
Recombinant Human Betacellulin |
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7-00225 | CHI Scientific | 1mg | Ask for price |
Betacellulin antibody |
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70R-BR013 | Fitzgerald | 50 ug | EUR 327.6 |
Description: Affinity purified Rabbit polyclonal Betacellulin antibody |
Betacellulin protein |
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30R-AB028 | Fitzgerald | 20 ug | EUR 327.6 |
Description: Purified recombinant Human Betacellulin protein |
Bovine Betacellulin |
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ARU020 | GroPep | 20 µg | EUR 303.6 |
Bovine Betacellulin |
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ARU100 | GroPep | 100 µg | EUR 415.2 |
Betacellulin, Mouse |
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HY-P7329 | MedChemExpress | 50ug | EUR 734.4 |
Human Betacellulin (bTC) Protein |
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20-abx065524 | Abbexa |
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Betacellulin (HEK293-expressed), Human |
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HY-P7328 | MedChemExpress | 10ug | EUR 280.8 |
Recombinant Human Betacellulin Protein |
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PROTP35070-2 | BosterBio | 20ug | EUR 380.4 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST μ-form |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST p-form |
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GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
Recombinant Bovine Betacellulin |
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7-00226 | CHI Scientific | 5µg | Ask for price |
Recombinant Bovine Betacellulin |
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7-00227 | CHI Scientific | 20µg | Ask for price |
Recombinant Bovine Betacellulin |
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7-00228 | CHI Scientific | 1mg | Ask for price |
Betacellulin Recombinant Protein |
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40-192-0005mg | ProSci | 0.005 mg | EUR 311.1 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Betacellulin Recombinant Protein |
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40-192-002mg | ProSci | 0.02 mg | EUR 437.1 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Betacellulin Recombinant Protein |
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91-592 | ProSci | 0.05 mg | EUR 651.3 |
Description: Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Betacellulin is characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family. Betacellulin is expressed in several tissues and tumor cells including kidney, uterus, liver, pancreas and small intestine. Betacellulin binds and activates ErbB-1 and ErbB-4 homodimers. Betacellulin is thought to play a role in the differentiation of pancreatic beta cells.Human and mouse mature BTC protein are 80% identical at the amino acid sequence level. Betacellulin is involved in many biological processes such as stimulating gastrointestinal growth. It is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen for a wide variety of cell types. |
Betacellulin Recombinant Protein |
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40-578-0005mg | ProSci | 0.005 mg | EUR 311.1 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Betacellulin Recombinant Protein |
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40-578-002mg | ProSci | 0.02 mg | EUR 437.1 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Betacellulin (bTC) Antibody |
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20-abx100739 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx100740 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx171411 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx175568 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx175569 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx175570 | Abbexa |
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Betacellulin (bTC) Antibody |
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20-abx175571 | Abbexa |
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Betacellulin (BTC) Antibody |
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20-abx111218 | Abbexa |
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Betacellulin (BTC) Antibody |
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abx230883-100ug | Abbexa | 100 ug | EUR 577.2 |
Betacellulin Recombinant Protein |
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96-830 | ProSci | 0.05 mg | EUR 714.3 |
Description: Probetacellulin can be cleaved into the Betacellulin (BTC) that is a single-pass type I membrane protein containing 1 EGF-like domain. Predominantly expressed in pancreas and small intestine,Betacellulin (BTC) is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. As a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells, Betacellulin (BTC) is also the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Betacellulin (BTC) was originally identified as a growth-promoting factor in mouse pancreatic beta-cell carcinoma cell line and has since been identified in humans. The amino acid sequence of mature mBTC is 82.5%, identical with that of human BTC (hBTC), and both exhibit significant overall similarity with other members of the EGF family. |
Betacellulin, murine (mouse) |
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RC238-23 | Bio Basic | 5ug | EUR 125.26 |
Recombinant Betacellulin (bTC) |
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4-RPA112Hu01 | Cloud-Clone |
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Description: Recombinant Human Betacellulin expressed in: E.coli |
Recombinant Betacellulin (bTC) |
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4-RPA112Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Betacellulin expressed in: E.coli |
Betacellulin Antibody / BTC |
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RQ4417 | NSJ Bioreagents | 100 ug | EUR 419 |
BTC Antibody / Betacellulin |
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RQ4539 | NSJ Bioreagents | 100ug | EUR 419 |
Betacellulin, Murine Recombinant |
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7119-10 | Biovision | each | EUR 235.2 |
Betacellulin, Murine Recombinant |
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7119-50 | Biovision | each | EUR 810 |
BTC Antibody / Betacellulin |
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F54607-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
BTC Antibody / Betacellulin |
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F54607-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
Human Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Hu-48T | DL Develop | 48T | EUR 574.8 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Hu-96T | DL Develop | 96T | EUR 745.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Human Betacellulin, BTC ELISA Kit |
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DEIA089 | Creative Diagnostics | 10 plates | EUR 3126 |
Description: This assay is a sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). It is developed for quantitative measurement of human BTC in serum, plasma and other biological fluids. |
Human Betacellulin (bTC) CLIA Kit |
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abx196482-96tests | Abbexa | 96 tests | EUR 990 |
Human Betacellulin (BTC) ELISA Kit |
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abx570040-96tests | Abbexa | 96 tests | EUR 801.6 |
Human Betacellulin (bTC) Protein (Active) |
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20-abx655563 | Abbexa |
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Human Betacellulin (BTC) CLIA Kit |
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20-abx491043 | Abbexa |
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Human Betacellulin (BTC) ELISA Kit |
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abx250182-96tests | Abbexa | 96 tests | EUR 801.6 |
Betacellulin (bTC) Polyclonal Antibody (Human) |
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4-PAA112Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC) |
Human Betacellulin/BTC ELISA Kit |
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LF-EK50996 | Abfrontier | 1×96T | EUR 777.6 |
Human BTC(Betacellulin) ELISA Kit |
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EH0044 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
BTC Betacellulin Human Recombinant Protein |
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PROTP35070-1 | BosterBio | Regular: 20ug | EUR 380.4 |
Description: Betacellulin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9 kDa. ;Betacellulin Human Recombinant is purified by proprietary chromatographic techniques. |
Human Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 600 |
Human Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 830.4 |
Human Betacellulin (bTC) ELISA Kit |
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RD-bTC-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 573.6 |
Human Betacellulin (bTC) ELISA Kit |
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RD-bTC-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 794.4 |
Human Betacellulin (bTC) ELISA Kit |
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SEA112Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5128.02 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
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SEA112Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 527.48 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
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SEA112Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 702.12 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
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SEA112Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2799.54 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
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4-SEA112Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Betacellulin (bTC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species. |
Human Betacellulin(BTC)ELISA Kit |
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YLA3880HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
Human Betacellulin(BTC)ELISA Kit |
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YLA3880HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
Mouse Betacellulin (bTC) Protein |
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20-abx065525 | Abbexa |
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Rat Betacellulin (bTC) Protein |
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20-abx652663 | Abbexa |
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Cow Betacellulin (bTC) Protein |
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20-abx652665 | Abbexa |
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Chicken Betacellulin (bTC) Protein |
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20-abx652666 | Abbexa |
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Betacellulin (bTC) Antibody (FITC) |
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20-abx274036 | Abbexa |
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Betacellulin (bTC) Antibody (Biotin) |
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20-abx271925 | Abbexa |
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Betacellulin (bTC) Antibody (Biotin) |
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20-abx272658 | Abbexa |
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Betacellulin (HEK293-expressed), Mouse |
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HY-P7142 | MedChemExpress | 50ug | EUR 639.6 |
Rat Betacellulin antiserum (Rabbit) |
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PAAQ1 | GroPep | 100 µl | EUR 358.8 |
Bovine Betacellulin antiserum (Rabbit) |
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PAAR1 | GroPep | 100 µl | EUR 358.8 |
Recombinant Murine Betacellulin Protein |
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PROTQ05928-1 | BosterBio | 20ug | EUR 380.4 |
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
ELISA kit for Human BTC (Betacellulin) |
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E-EL-H0570 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
Description: A sandwich ELISA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
CLIA kit for Human BTC (Betacellulin) |
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E-CL-H0444 | Elabscience Biotech | 1 plate of 96 wells | EUR 700.8 |
Description: A sandwich CLIA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Human bTC (Betacellulin) |
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ELK1403 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
Description: A sandwich ELISA kit for detection of Betacellulin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Human Betacellulin/BTC PicoKine ELISA Kit |
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EK0980 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of human Betacellulin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
ELISA kit for Human Betacellulin/BTC |
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EK5454 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
Betacellulin (bTC) Polyclonal Antibody (Human), APC |
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4-PAA112Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with APC. |
Betacellulin (bTC) Polyclonal Antibody (Human), Biotinylated |
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4-PAA112Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with Biotin. |
Betacellulin (bTC) Polyclonal Antibody (Human), Cy3 |
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4-PAA112Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with Cy3. |
Betacellulin (bTC) Polyclonal Antibody (Human), FITC |
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4-PAA112Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with FITC. |
Betacellulin (bTC) Polyclonal Antibody (Human), HRP |
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4-PAA112Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with HRP. |
Betacellulin (bTC) Polyclonal Antibody (Human), PE |
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4-PAA112Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with PE. |
Nori® Human Betacellulin ELISA Kit |
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GR106276 | Genorise Scientific | 96-well | EUR 553.2 |
Human Probetacellulin [Cleaved into: Betacellulin protein (BTC) |
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1-CSB-EP002853HU | Cusabio |
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Description: Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein(BTC) expressed in E.coli |
Betacellulin ELISA Kit (Human) : 96 Wells (OKAG00006) |
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OKAG00006 | Aviva Systems Biology | 96 Wells | EUR 715.2 |
Description: Description of target: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 8 pg/mL |
Betacellulin (bTC) Polyclonal Antibody (Human), APC-Cy7 |
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4-PAA112Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
BTC Betacellulin Human Recombinant Protein, His Tag |
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PROTP35070 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: BTC Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (32-111) and having a molecular mass of 11.3 kDa.;BTC is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Mouse Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Mu-48T | DL Develop | 48T | EUR 519.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Mu-96T | DL Develop | 96T | EUR 669.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Rat Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Ra-48T | DL Develop | 48T | EUR 609.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Rat Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates,cell culture supernates or other biological fluids. |
Rat Betacellulin (bTC) ELISA Kit |
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DLR-bTC-Ra-96T | DL Develop | 96T | EUR 793.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Rat Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates,cell culture supernates or other biological fluids. |
Mouse Betacellulin (BTC) ELISA Kit |
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20-abx153708 | Abbexa |
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Pig Betacellulin (BTC) ELISA Kit |
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abx361663-96tests | Abbexa | 96 tests | EUR 990 |
Rabbit Betacellulin (BTC) ELISA Kit |
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abx363832-96tests | Abbexa | 96 tests | EUR 990 |
Monkey Betacellulin (BTC) ELISA Kit |
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abx359865-96tests | Abbexa | 96 tests | EUR 990 |
Rat Betacellulin (BTC) ELISA Kit |
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abx576495-96tests | Abbexa | 96 tests | EUR 990 |
Chicken Betacellulin (BTC) ELISA Kit |
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abx574267-96tests | Abbexa | 96 tests | EUR 990 |
Mouse Betacellulin (BTC) ELISA Kit |
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abx574631-96tests | Abbexa | 96 tests | EUR 801.6 |
Cow Betacellulin (BTC) ELISA Kit |
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abx575529-96tests | Abbexa | 96 tests | EUR 1093.2 |
Mouse Betacellulin (BTC) CLIA Kit |
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20-abx491044 | Abbexa |
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Mouse Betacellulin (BTC) ELISA Kit |
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abx253974-96tests | Abbexa | 96 tests | EUR 801.6 |
Rat Betacellulin (BTC) ELISA Kit |
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abx255590-96tests | Abbexa | 96 tests | EUR 801.6 |
Betacellulin (bTC) Polyclonal Antibody (Mouse) |
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4-PAA112Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC) |
Betacellulin (bTC) Polyclonal Antibody (Rat) |
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4-PAA112Ra01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC) |
BTC Betacellulin Mouse Recombinant Protein |
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PROTQ05928 | BosterBio | Regular: 20ug | EUR 380.4 |
Description: BTC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 80 amino acids and having a molecular mass of 9.0kDa. ;The BTC is purified by proprietary chromatographic techniques. |
BTC Betacellulin Bovine Recombinant Protein |
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PROTQ9TTC5 | BosterBio | Regular: 20ug | EUR 380.4 |
Description: Betacellulin Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9003 Dalton. ;Betacellulin Bovine Recombinant is purified by proprietary chromatographic techniques. |
Mouse Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
Mouse Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 736.8 |
Rat Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 640.8 |
Rat Betacellulin (bTC) ELISA Kit |
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RDR-bTC-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 890.4 |
Mouse Betacellulin (bTC) ELISA Kit |
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RD-bTC-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 511.2 |
Mouse Betacellulin (bTC) ELISA Kit |
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RD-bTC-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 704.4 |
Rat Betacellulin (bTC) ELISA Kit |
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RD-bTC-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 613.2 |
Rat Betacellulin (bTC) ELISA Kit |
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RD-bTC-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 850.8 |
Mouse Betacellulin (bTC) ELISA Kit |
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SEA112Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4452.58 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Betacellulin (bTC) ELISA Kit |
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SEA112Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 471.86 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Betacellulin (bTC) ELISA Kit |
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SEA112Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 622.66 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Betacellulin (bTC) ELISA Kit |
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SEA112Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2441.95 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Mouse Betacellulin (bTC) ELISA Kit |
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4-SEA112Mu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Betacellulin (bTC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Nori® Human Betacellulin ELISA Kit (2 plates) |
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GR106276-2 | Genorise Scientific | 2 x 96-well | EUR 998.4 |
Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-100ug |
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QP10416-ec-100ug | EnQuireBio | 100ug | EUR 1185.6 |
Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-20ug |
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QP10416-ec-20ug | EnQuireBio | 20ug | EUR 348 |
Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-250ug |
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QP10416-ec-250ug | EnQuireBio | 250ug | EUR 2077.2 |
Recombinant Human BTC/ Betacellulin Protein, Untagged, E.coli-5ug |
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QP10416-ec-5ug | EnQuireBio | 5ug | EUR 184.8 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-100ug |
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QP5728-ec-100ug | EnQuireBio | 100ug | EUR 501.6 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-10ug |
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QP5728-ec-10ug | EnQuireBio | 10ug | EUR 186 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-1mg |
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QP5728-ec-1mg | EnQuireBio | 1mg | EUR 2013.6 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-200ug |
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QP5728-ec-200ug | EnQuireBio | 200ug | EUR 762 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-500ug |
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QP5728-ec-500ug | EnQuireBio | 500ug | EUR 1263.6 |
Recombinant Human BTC/ Betacellulin Protein, His, E.coli-50ug |
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QP5728-ec-50ug | EnQuireBio | 50ug | EUR 337.2 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-100ug |
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QP5728-ye-100ug | EnQuireBio | 100ug | EUR 501.6 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-10ug |
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QP5728-ye-10ug | EnQuireBio | 10ug | EUR 186 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-1mg |
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QP5728-ye-1mg | EnQuireBio | 1mg | EUR 2013.6 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-200ug |
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QP5728-ye-200ug | EnQuireBio | 200ug | EUR 762 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-500ug |
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QP5728-ye-500ug | EnQuireBio | 500ug | EUR 1263.6 |
Recombinant Human BTC/ Betacellulin Protein, His, Yeast-50ug |
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QP5728-ye-50ug | EnQuireBio | 50ug | EUR 337.2 |
ELISA kit for Mouse BTC (Betacellulin) |
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E-EL-M0181 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
Description: A sandwich ELISA kit for quantitative measurement of Mouse BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Rat BTC (Betacellulin) |
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E-EL-R0101 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
Description: A sandwich ELISA kit for quantitative measurement of Rat BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
Recombinant Mouse Betacellulin/BTC (N-6His) |
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C747-10ug | Novoprotein | 10ug | EUR 187.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse Betacellulin/BTC (N-6His) |
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C747-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse Betacellulin/BTC (N-6His) |
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C747-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse Betacellulin/BTC (N-6His) |
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C747-50ug | Novoprotein | 50ug | EUR 442.8 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
CLIA kit for Mouse BTC (Betacellulin) |
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E-CL-M0133 | Elabscience Biotech | 1 plate of 96 wells | EUR 700.8 |
Description: A sandwich CLIA kit for quantitative measurement of Mouse BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Mouse bTC (Betacellulin) |
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ELK1236 | ELK Biotech | 1 plate of 96 wells | EUR 446.4 |
Description: A sandwich ELISA kit for detection of Betacellulin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Mouse Betacellulin/BTC PicoKine ELISA Kit |
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EK1193 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of mouse BTC in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
ELISA kit for Mouse Betacellulin/BTC |
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EK5523 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
ELISA kit for Rat Betacellulin/BTC |
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EK5582 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Betacellulin/BTC in samples from serum, plasma, tissue homogenates and other biological fluids. |
Guinea pig Betacellulin (BTC) ELISA Kit |
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abx357846-96tests | Abbexa | 96 tests | EUR 990 |
Betacellulin/BTC ELISA Kit (Mouse) (OKBB00530) |
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OKBB00530 | Aviva Systems Biology | 96 Wells | EUR 606 |
Description: Description of target: Betacellulin, also known as BTC is a protein that in humans is encoded by the BTC gene. This gene is mapped to 4q13.3. The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. It is the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. This protein is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
Betacellulin (bTC) Polyclonal Antibody (Mouse), APC |
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4-PAA112Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with APC. |
Betacellulin (bTC) Polyclonal Antibody (Mouse), Biotinylated |
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4-PAA112Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with Biotin. |
Betacellulin (bTC) Polyclonal Antibody (Mouse), Cy3 |
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4-PAA112Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with Cy3. |
Betacellulin (bTC) Polyclonal Antibody (Mouse), FITC |
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4-PAA112Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with FITC. |
Betacellulin (bTC) Polyclonal Antibody (Mouse), HRP |
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4-PAA112Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with HRP. |
Betacellulin (bTC) Polyclonal Antibody (Mouse), PE |
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4-PAA112Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with PE. |
Betacellulin (bTC) Polyclonal Antibody (Rat), APC |
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4-PAA112Ra01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with APC. |
Betacellulin (bTC) Polyclonal Antibody (Rat), Biotinylated |
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4-PAA112Ra01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with Biotin. |
Betacellulin (bTC) Polyclonal Antibody (Rat), Cy3 |
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4-PAA112Ra01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with Cy3. |
Betacellulin (bTC) Polyclonal Antibody (Rat), FITC |
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4-PAA112Ra01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with FITC. |
Betacellulin (bTC) Polyclonal Antibody (Rat), HRP |
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4-PAA112Ra01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with HRP. |
Betacellulin (bTC) Polyclonal Antibody (Rat), PE |
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4-PAA112Ra01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with PE. |
Mouse Betacellulin/BTC(Beta Cellulin) ELISA Kit |
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EM0021 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 4.688pg/ml |
Betacellulin (bTC) Polyclonal Antibody (Mouse), APC-Cy7 |
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4-PAA112Mu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
Betacellulin (bTC) Polyclonal Antibody (Rat), APC-Cy7 |
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4-PAA112Ra01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Betacellulin (bTC). This antibody is labeled with APC-Cy7. |
Recombinant Betacellulin Protein (Asp 32-Tyr 111) [Fc] |
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VAng-1124Lsx-1mg | Creative Biolabs | 1 mg | EUR 7318.8 |
Description: Human Betacellulin, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH11618) |
Recombinant Betacellulin Protein (Asp 32-Tyr 111) [Fc] |
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VAng-1124Lsx-50g | Creative Biolabs | 50 µg | EUR 1215.6 |
Description: Human Betacellulin, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH11618) |
Betacellulin/BTC ELISA Kit| Mouse Beta Cellulin ELISA Kit |
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EF012837 | Lifescience Market | 96 Tests | EUR 826.8 |
Anti-Human IgG |
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DB-173-0.1 | DB Biotech | 100 μl | EUR 254.4 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-173-0.2 | DB Biotech | 200 μl | EUR 357.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-173-0.5 | DB Biotech | 500 μl | EUR 460.8 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-173-1 | DB Biotech | 1 ml | EUR 735.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-173-RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
Anti-Human IgG |
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DB-173-RTU-7 | DB Biotech | 7 ml | EUR 277.2 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
Anti-Human IgG |
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DB-174-0.1 | DB Biotech | 100 μl | EUR 254.4 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-174-0.2 | DB Biotech | 200 μl | EUR 357.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-174-0.5 | DB Biotech | 500 μl | EUR 460.8 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-174-1 | DB Biotech | 1 ml | EUR 735.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-Human IgG |
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DB-174-RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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